Supercritical CO2 Extraction Machine
Suzhou Pharma Machinery Co., Ltd. is a leading provider of turnkey projects for pharmaceutical, food, herbal, cosmetic, electronics, and chemical plants. Our extensive cleanroom expertise allows us to meet the precise needs of clients across diverse sectors, including medical, pharmaceutical, biotechnology, and cosmetics. In addition to turnkey projects, we also provide cleanroom equipment such as transfer windows, air showers, clean benches, and laminar flow hoods. We offer a comprehensive range of services for any cleanroom project you require.
Why Choose Us
Professional Certificates
We have obtained numerous authoritative certifications, including trademark registration, LED lamp certification, supercritical CO₂ extraction equipment certification, cleanroom system certification, filter material testing equipment certification, and SGS and CE certifications.
24-Hour Online Service
We provide all customers with 24/7 pre-sales and after-sales service. We have established a collaborative team of sales and technical engineers to ensure timely answers to customer questions and provide professional technical support.
Customized Services
Regardless of the scale of cleanroom projects, we offer comprehensive, customized solutions tailored to meet the specific requirements of various application scenarios and precisely address diverse customer needs.
Professional Team
We have comprehensive infrastructure and an experienced team of professionals with extensive expertise in various industries, including medical, pharmaceutical, biotechnology, and cosmetics. We provide efficient and systematic management and technical support in cleanroom-related areas.
Specification
|
Name |
Supercritical CO2 Extraction System |
|
Extraction Kettle |
SUS304, 50MPa(adjustable), Capacity can be customized, 100mL~1000L |
|
Separation Kettle |
SUS304, 30MPa(adjustable), According to the extraction kettle volume configuration, generally 50mL~800L |
|
Purification System |
16MPa |
|
Commingler |
SUS304, According to the overall scheme configuration, 4L~6000L |
|
Heat Exchange System |
35-100MPa |
|
Cooling System |
5-7℃ |
|
Safety System |
Crowbar protection |
|
Recovery System |
According to the size of the equipment, the corresponding recovery system is configured to recover excess CO2 and reduce loss |
|
Regulating Valve |
SUS304 |
|
Pipe Fitting |
SUS304, 50MPa |

Efficient separation: Supercritical CO2 extraction machine combines extraction and separation, improving efficiency through pressure reduction or temperature variation.
Pressure and temperature control: Pressure and temperature are precisely adjusted based on material and compound characteristics, ensuring efficiency and quality.
Safety protection: Equipped with overpressure protection gauges and valves to prevent damage.
User-friendly interface: An intuitive interface and flowchart are used for easy operation and understanding.
Wide applicability: Supercritical CO2 extraction machine is widely used in natural products, food, fragrance, and pharmaceutical industries.
Types of Supercritical CO2 Extraction Machine
Single Supercritical CO2 Extraction Machine
This configuration is widely used in labs for testing supercritical CO2 extraction conditions before starting industrial production. Very small laboratory systems (extractor volume from 50 to 1000 mL) are generally used for extract analysis but are not useful for deriving process conditions (pressure, temperature, flow rate, kinetics).
Double Supercritical CO2 Extraction Machine
This configuration was an important step towards greater process efficiency for supercritical CO2 extraction, but only when fully automated. Only with automation is it possible to exploit the advantages of semi-continuous extraction, in which there are no dead times between one extraction and another (as happens with the single extractor configuration). One extractor is unloaded and reloaded while the other one is under extraction.
Triple Supercritical CO2 Extraction Machine
This configuration is the most used in large systems, as it considerably increases extraction performance, exploiting the advantages of overlapping process for supercritical CO2 extraction, +50% compared to the configuration with double extractor. This configuration requires a very high level of automation.
Extraction System: Typically consists of single or multiple extraction vessels, with 2 to 3 extraction vessels being the standard configuration (up to 6 can be configured).
Separation System: Typically consists of single or multiple separation vessels. Popular CO2 extraction machines usually have 2 to 3 extraction vessels and 3 separators.
Supercritical Fluid Generation and Closed-Loop Operation System: This system, made up of a CO2 high-pressure pump, filters, mixers, and fluid transmission lines, generates supercritical CO2 fluid. The CO2 pump pressurizes the high-pressure liquid into the supercritical fluid state, which then dissolves and extracts targets from biomass. The extracted substances are separated via depressurization and returned to liquid form for recirculation.
Heat Exchange System: Responsible for providing the necessary energy to regulate the temperatures of the extraction and separation vessels.
Control System: A CNC control system for real-time, automatic regulation of the extraction machine's temperature, pressure, and flow rate.

Basic Principles of Supercritical CO2 Extraction Machine
The supercritical CO2 extraction machine principle typically involves the following steps
Pressurization
CO2 is compressed to reach its supercritical state.
Extraction
The supercritical CO2 flows through a vessel containing the raw material, dissolving target compounds.
Separation
he CO2-extract mixture enters a separator where pressure is reduced, causing the CO2 to return to a gaseous state and precipitating the extracted compounds.
Collection
The extracted compounds are collected, while the gaseous CO2 is recycled back into the system.
Supercritical CO2 Extraction Machine Application Areas
Pharmaceuticals
Extraction of active pharmaceutical ingredients from natural sources.
Food processing
Decaffeination of coffee and tea, extraction of flavors and fragrances.
Cosmetics and personal care
Extraction of natural ingredients and essential oils.
Environmental remediation
Removal of contaminants from soil and water.
Nutraceuticals
Extraction of bioactive compounds from plants and herbs.
Materials science
Production of advanced materials and nanoparticles.
Our Service
7 days shipments
Fast production and most of the materials have stock in our warehouse, we can ship within 7 days after you put on order, except the special made air conditioner.
Happiness Design
Make you own design under our help with happiness and easily satisfy you.
"LEGO" installation
All the installation parts equipped with 3D video, "0" experience to finish by yourself.
Overseas standby
Overseas team is standby at any time for your service if you need our people for work
Bank credit service
We can supply max. 20% credit for clients without any special request to make you earn money then give back the investment.
24 hours on-line service
All of customer will enjoy 24 hours pre-sale and after sale online service, we build a discussing group that both salesman and engineer join us to answer your question and provide technical support.
Packaging and Shipping
|
Packaging |
Wooden box, PE film |
|
Transportation methods |
Road transport, rail transport, sea transport, air transport |
Video
Our Certificate





We're well-known as one of the leading supercritical co2 extraction machine manufacturers and suppliers in China. If you're going to wholesale customized supercritical co2 extraction machine at competitive price, welcome to get quotation from our factory.
supercritical co2 extraction machine





